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The impact of aging on neurological diseases in the elderly: molecular mechanisms and therapeutic perspectives
The p62/SQSTM1 (sequestosome 1) protein, which acts as a cargo receptor for autophagic degradation of ubiquitinated proteins, is up-regulated by various stressors
Steele, Dalton

If you look at the culprit from the problem for almost any disease, any condition, that we are dealing with today, it starts with oxidative stress

Ford R, Goodacre A, Siciliano M, Claypool K, H-L S, Chan J, Andreeff M

doi: 10.1155/2017/1813086 129 HongzhiDXiaoyingHYujieGLeCYuhuanMDahuiLet al