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When Wnt pathway activation occurs, Twa1 translocates to the nucleus, and its conserved CRA (CT11-RanBPM) domain is required for its interaction with -catenin, which promotes -catenin nuclear retention and increases Wnt/-catenin downstream target gene expression

Yimao Wu, Xiaoyan Chen, Zichang Chen, Yunqi Ma

doi: 10.1038/npp.2009.110

Larder CE, Iskandar MM, Sabally K, Kubow S

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Known in research circles as the "Body Protection Compound," this peptide is turning heads for its ability to accelerate recovery, reduce inflammation at its root, and stimulate tissue regeneration without suppressing the immune system