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Metformin is of great focus because of its high safety, low side effects, and various effects other than lowering blood sugar, such as anti-inflammation, ant...

Until stronger prospective safety data are available, counseling should be individualized, agent-specific, and centered on pregnancy intention, contraceptive reliability, metabolic risk, and shared decision-making.

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Methods This retrospective cohort study included data on US adults with T2D receiving SGLT2i from Komodos Healthcare Map from January 1, 2017, to June 30, 2023