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PMCID: PMC10801460

Timing: The timing of taking Janumet can depend on the specific formulation
Clinicians, therefore, try smaller increments to preserve adherence and allow muscle-preserving lifestyle work to continue alongside medication
After injection, properly dispose of the needle in an FDA-cleared sharps container and replace the pen cap

These typically resolve within 12 weeks as tolerance builds

Safe and science-backed approach using FDA-approved medications