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UK regulatory guidance (MHRA, NICE, BNF) advises against GLP-1 use whilst breastfeeding owing to lack of robust human safety studies

GLP-1RAs effects are relevant to MS, with potential to modulate inflammation, promote remyelination, and to stabilize the BBB

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Moulton CD, Pickup JC, Amiel SA, Winkley K, Ismail K

Some researchers are exploring whether compounds like AOD-9604 combined with tirzepatide might offer complementary mechanisms without the cardiovascular concerns of stimulant addition

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