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While Novo paid a significant 80% premium for Dicerna, this was a long-term bet on a new technology, and it fit Novos core areas on cardiometabolic and rare diseases

When patients lose substantial weighta common occurrence with GLP-1 receptor agoniststhis can trigger changes in hormone levels, including alterations in insulin sensitivity, sex hormones, and inflammatory markers

Wahlqvist ML, Lee M-S, Hsu C-C, Chuang S-Y, Lee J-T, Tsai H-N

Aortic pulsatility index predicts clinical outcomes in heart failure: a sub-analysis of the ESCAPE trial

Addressing air bubbles now prevents cumulative loss of therapeutic benefit

Phentermine should be discontinued in case of new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema