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In SUSTAIN-6 trial similar effects in MACE risk reduction, glycemic control and hypoglycemia rates were observed in patients receiving 0.5 mg semaglutide once weekly and in those receiving 1 mg once weekly (43)
doi: 10.1124/pr.115.011395 111 BullockBPHellerRSHabenerJF
Substitution with the non-native amino acid aminoisobutyric acid at position 2 confers resistance to DPP-IV degradation [17]
