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doi:10.1016/S2213-8587(20)30038-3 25

(2) no arm dedicated to the combination therapy of SGLT-2i and GLP-1RAs

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Obesity (Silver Spring) 25311316

A total of 577 patients were randomly assigned (1:1:1) to receive once-weekly dulaglutide (1.5 mg), once-weekly dulaglutide (0.75 mg), or daily insulin glargine as basal therapy, all in combination with insulin lispro, for 52 weeks

Their primary sequences share substantial homology because both were engineered from the broader exendin/GIP scaffold tradition