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Importantly, Zepbound may decrease the effectiveness of oral contraceptives, necessitating the use of a non-oral method or additional barrier contraception for 4 weeks after initiating treatment and for 4 weeks after each dose increase

The injection is to be taken once weekly, on the same day each week, at whatever time works best for you, with or without meals

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Summary: Wegovy is not contraindicated in lupus patients, but requires individualised assessment by healthcare professionals considering disease activity, organ involvement, and concurrent medications

This medication is highly teratogenic (can cause birth defects) and requires participation in the MHRA Pregnancy Prevention Programme for women of childbearing potential, along with regular monitoring of blood tests

Patients also have access to PlexusDx oral tirzepatide ($279/mo), semaglutide injection ($149/mo), and the proprietary GLP-Squared dual-compound protocol if genetic testing predicts benefit from both peptides in a single, controlled formulation