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If disease activity remains inadequately controlled, treatment should escalate to combination conventional synthetic DMARDs or biological agents following a treat-to-target approach
Diabetes Obes Metab (2017) 19:124251
NICE guidance (NG100) recommends disease-modifying antirheumatic drugs (DMARDs) as standard care, with methotrexate as first-line therapy
This massive spike in pharmacy costs is placing unprecedented strain on employer-sponsored health plans
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