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Christofi, F

In the present study, it was observed that the liraglutide/GLP-1R axis acts in chondrocytes and macrophages to decrease inflammation and catabolism in vitro, which was confirmed by pain alleviation in vivo in mouse OA inflammatory pain model

Despite showing an increase in SIBO likelihood, the numbers were minimal (fewer than 0.02%), and the study did not prove causation, only a correlation based on a yes/no diagnosis

When administered, Semaglutide binds to GLP-1 receptors, stimulating the pancreas to enhance insulin secretion in response to meals, while simultaneously reducing glucagon release, helping to prevent excessive blood sugar levels
