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Preclinical and preliminary clinical evidence of semaglutides potential beneficial effects on various substance use disorders led us to evaluate if it pertained to CUD

Mechanistically, these effects are linked to GLP-1 RA-mediated suppression of inflammatory pathways, modulation of skeletal muscle metabolism, and preservation of mitochondrial function, thereby influencing insulin resistance

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Enhance the effects of GLP-1 medications with a supportive meal plan for metabolic health