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Both meta-analyses and review of the literature indicate that further controlled studies are required to confirm the clinical benefits of high-frequency GES

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doi: 10.1503/cmaj.081040

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Products that feel medical or punitive will struggle to scale beyond an early adopter audience

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In addition, GLP-1 can reduce liver cholesterol accumulation by inhibiting SREBP2 and PCSK9, and reduce liver bile acid synthesis by weakening the negative feedback inhibition of bile acid after inhibiting FXR

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In this work, therapeutic inertia was observed in nearly 40% of the study population

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