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Hepatic gluconeogenesis and insulin sensitivity were improved in ob/ob mice treated with recombinant adenovirus expressing GLP-1 (rAd-GLP-1) [22]

But for some, the inflammation never fully settles in part because their fat tissue is producing inflammatory molecules around the clock, undercutting the effect of the biologic

Increased GLP-1 after bariatric surgery may be the result of rapid gastrointestinal nutrient input and increased plasma BAs (164)