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Hypoglycemia (low blood sugar) is primarily a risk for patients taking concurrent insulin or sulfonylureas, as tirzepatide itself has a glucose-dependent mechanism that generally limits hypoglycemia risk when used alone

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Semaglutide can also improve HF outcomes by impacting the pathophysiology of HF with preserved ejection fraction (HFpEF) patients based on three new substudies from the STEP-HFpEF program

In addition to aiding in weight loss, GLP-1 agonists can improve blood sugar control and offer cardiovascular and kidney health benefits, particularly for those managing diabetes
