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Your appetite suppression gradually decreases over 710 days as the medication's level in your blood drops

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The SURPASS-2 trial (A Study of Tirzepatide versus Semaglutide Once Weekly as an Add-On Therapy to Metformin in Participants with Type 2 Diabetes) compared the efficacy of different doses of tirzepatide with semaglutide 1 mg in patients with poorly controlled diabetes on metformin monotherapy

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