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This could point to the defendants understanding that their GLP-1 drugs can indeed lead to vision loss in some patients

107,203 The physiological relevance of GLP-1 metabolites remains an area of controversy

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Overall prescribing rates (GLP-1 RA prescriptions per total prescriptions) increased slightly from September to December 2025 (+5.0%)

This was accompanied by improvements in menstrual frequency and ovulation markers, suggesting weight loss and the alleviation of central obesity are likely critical mediators of reproductive benefit (109)