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Description
Recent CV outcome trials utilizing GLP-1RAs have also investigated renal outcomes

Long-Term Outcomes (After 1 Year) Long-term adherence to semaglutide treatment can lead to remarkable and sustained weight loss

Longer term For longer protocols, review metabolic, kidney, liver, and cardiovascular trends every 3-6 months with a clinician

Semaglutide acetate has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing -synuclein aggregation) and improving hepatic steatosis

NICE NG246: Medicines and surgery Overweight and obesity management

GIPs effects on appetite and brain signaling are less clear than GLP-1s
