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doi: 10.1210/jc.2015-2335

Volume depletion and hypotension can occur with SGLT2 inhibitors due to osmotic diuresis, particularly in elderly patients, those taking diuretics, or individuals with impaired renal function

Tirzepatide is approved as Mounjaro for T2D and as Zepbound for chronic weight management and, notably by the FDA, for treatment of moderate to severe OSA in adults with obesity

2 For a diagnosis to be made, it should include two of the three following: (i) hyperandrogenism, whether clinical or biochemical, (ii) ovulatory dysfunction (this also includes cases of regular cycles where anovulation is evaluated by measuring progesterone levels), and (iii) polycystic ovaries on ultrasound, the latter could be replaced by raised levels of anti-Mllerian hormone (AMH) in adults

Hadjiyanni I, Siminovitch KA, Danska JS, Drucker DJ
