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COPD pathogenesis is related to direct toxicity of inhaled irritants, pro-inflammatory effects of ROS, protease/anti-protease imbalance, and impaired immune function in the lungs of smokers

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Whether preferring the rugged spontaneity of Backwoods or the refined consistency of Traditional Cigars, sampling both types and consulting with a knowledgeable tobacconist can help in making an informed choice

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