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This class of tyrosine kinase inhibitors is effective against lung cancers that carry mutations in the epidermal growth factor receptor ( EGFR ) gene 3,4,5

Am J Respir Crit Care Med 2015;191620-5

The latest data available for adults aged 35 years and older show that, of the 12 cancers determined to be caused by smoking, those most likely to be attributed to cigarette smoking were cancers of the lung, bronchus, and trachea (80.2%) and the larynx (76.6%)

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