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We found that many of these flavorings increase free radicals, but a few decreased them, as well, which raises the possibility that maybe there are things you can add to these liquids that could reduce radical production and might make them safer. Richie said

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Medical Journal of Australia, 2014

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Smoking causes more deaths each year than the following causes combined: human immunodeficiency virus (HIV), illegal drug use, alcohol use, motor vehicle injuries and firearm-related incidents