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Flavor selection, pouch format, pouch count, packaging, and nicotine source differ between the product lines

The use of these products has increased exponentially acquiring epidemic proportions in developed countries, especially among the youth and children

Eight states have enacted similar legislation that has not yet taken effect

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"Given the negative health consequences of tobacco use and the unique harms associated with adolescent nicotine exposure, prevention of youth tobacco product use is crucial," the report's authors wrote.

A randomized crossover lab study (12 healthy men) found gums with nicotine and caffeine increased energy expenditure versus placebo