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Boules M, Li Z, Smith K, et al (2013) Diverse roles of neurotensin agonists in the central nervous system
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In addition, GDH inhibition also limits synaptic glutamate uptake (Whitelaw and Robinson 2013), whereas genetic deletion of GDH leads to impaired glutamine metabolism in cultured neurons (Hohnholt et al

It penetrates the cell membrane and disrupts internal cellular function, leading to regulated cell death

Methadone was generously supplied by the National Institute on Drug Abuse (NIDA, Rockville, MD)
