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The inability to dephosphorylate glucose 6-phosphate leads to an increase in the diversion of this sugar into the pentose phosphate pathway (PPP)
This study demonstrated that the inhibition of EZH2 suppresses EndMT, but the mechanism has not been explored in depth
Aging Cell 12 , 148155, (2013)

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Phase II study of personalized peptide vaccination for castration-resistant prostate cancer patients who failed in docetaxel-based chemotherapy

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