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The absence of mucin, a highly glycosylated polymeric protein in the mucous layer, makes an animal vulnerable to intestinal inflammation, which leads to the development of spontaneous colitis and confers a predisposition to the development of colorectal cancers (Fig

We explain these differences with the change in the staggering of the salt bridge D23-K28, characteristic for the U-shaped A 40 , from (i,i+2) in L-peptides to (i, i-2) in DRI peptides

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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Sabari JK, Leonardi GC, Shu CA, Umeton R, Montecalvo J, Ni A, Chen R, Dienstag J, Mrad C, Bergagnini I, et al