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Acetylation of lysine residues within histones relaxes chromatin structure, facilitates access of transcription factors to promoter regions and increases gene transcription

This may explain why susceptibility to de novo leukemia has been so difficult to explain in persons without any obvious exposures to leukemogenic agents, such as benzene and ionizing radiation

Foxo4dri is a senolytic peptide that disrupts the p53 gene, causing apoptosis in ageing cells

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Authors also thank Neeranjini Nallathamby for ideas and guidance

The concentration of nitroxide radical (mito-TEMPO) following oxidation of (mito-TEMPO-H) was measured in liver and kidney 24 h following AKI