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Description
FASEB J off Publ Fed Am Soc Exp Biol 27:50225033
Systemic reactions: Rapid heart rate, shortness of breath, or signs of anaphylaxis (hives, swelling, difficulty breathing) in rare cases

The most common starting protocol is 250 mcg twice daily
Pros: ready-to-use

That 2% difference might sound small, but it represents a meaningful increase in risk that becomes more significant when you factor in the broader category of gastrointestinal side effects

It takes more time in the chair, but the delivery is efficient and closely supervised
