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It was administered intraperitoneally at 25, 50 or 100 mg/kg for 21 days, and behavioral analyses focused on sociability and repetitive behaviors

While melanosis coli itself is generally not associated with serious health risks, it often raises concern due to its potential to mimic other colonic pathologies, such as colorectal neoplasms

[Google Scholar] 31.Massone C., Hofman-Wellenhof R., Chiodi S., Sola S

This side effect sparked the idea that melanocortin peptides might enhance sexual function

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