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Sex-dependent differential activation of NLRP3 and AIM2 inflammasomes in SLE macrophages

doi: 10.1016/j.ecoenv.2022.114410 19 ZhangEYangYChenSPengCLavinMFYeoAJet al

Zhiqiang Lin et al

(2) Synthesis of the isoprenoid tail: The isoprenoid tail of CoQ is synthesized through the cytosolic mevalonate pathway, which produces key precursors such as isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) 28,31

Future studies employing chromatin immunoprecipitation assays will be necessary to definitively test whether HIF-1 and/or c-Myc directly bind to the SLC16A1 promoter in SCs and how this is governed by SYK activity

Propionate is yet another important energy supply with an important function in the gluconeogenesis of PPCs, especially of the liver epithelial cells ( Faecalibacterium prausnitzii cannot be cultivated axenically in a medium without acetate (Rowland et al., 2018)