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However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)

FIGURE 13 In the aforementioned study by Hsieh and collaborators (Hsieh et al., 2017) that focused on the ischemic muscle model (achieved via removal of the femoral artery), the pro-angiogenic effects of BPC 157 are evident, given the increased expression, internalization of vascular endothelial growth factor receptor 2 (VEGFR2), and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)

[DOI] [PubMed] [Google Scholar] 104.Goncharova N.D., Khavinson B.K., Lapin B.A

This gives a specific marker-based explanation for why BPC-157 is discussed in tendon research rather than relying only on broad repair wording
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2019;17(4):5662, 78 pp
