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Meja et al., 2008

We propose that NADPH and GSSG convey TCA cycle status: decreasing the availability of acetyl-CoAeither from lipid or carbohydrate catabolismdampens NADPH production and disfavors glutathione reduction, with the increased GSSG ultimately rendering the ER lumen more oxidizing and protecting ER homeostasis

The conjugation of GSH with xenobiotics, including anti-cancer drugs, can result in either of two effects: xenobiotics may lose their harmful effects, or GSH conjugation may enhance their toxicity by inducing bioactivation

Gut Microbes 16, 2297860

Shanmugam V

J Neurochem 143:684696 Luangmonkong T, Suriguga S, Mutsaers HAM, Groothuis GMM, Olinga P, Boersema M (2018) Targeting oxidative stress for the treatment of liver fibrosis
