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Description
Cysteine depletion, which results in the intracellular exhaustion of glutathione, serves as a preliminary feature of the mechanism and triggers ferroptosis ( The biological features of ferroptosis are distinguished by the aggregation of iron and ROS, which reduces the level of cystine uptake and consumes GSH to inhibit the activities of system xc- and GPX4
Oxidative stress refers to a disruption in the balance between oxidant molecules and antioxidant defences, with a shift toward oxidant predominance
The role of immune cells and cytokines in intestinal wound healing
Despite short serum half-life, daily dosing produces robust, sustained tissue-repair effects in rodent models
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