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Hepatic parenchymal cell AML12 (#CRL-2254, ATCC) was cultured in special DMEM media with 10% FBS, 0.5% ITS-G and 40 ng/ml dexamethasone

The consequences of glutaminase inhibition have been studied in solid cancers with promising results ( Although data on the use of glutaminase inhibitor CB-839 in CLL are not available, Parlati et al

Randomized trials have demonstrated that exogenous melatonin can be of benefit in a number of sleep disease states including delayed sleep phase syndrome, non-24-hour sleep-wake syndrome, jet lag, and insomnia

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