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Tbx1 haploinsufficiency has no significant effect on the brain transcriptome We next sought to identify the transcriptional changes associated with the metabolic alterations identified in Tbx1 +/ mice
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This is because they have less body strength and may have other health problems

Although NNMT may affect nicotinamide levels and NAD+ pathways, the real impact in the body is still unclear

Biochemical and Physiological Aspects of Human Nutrition