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doi: 10.1111/nmo.12829 53 GuYLiLYangMLiuTSongXQinXet al

Oxidative stress is implicated in the pathophysiology of GU

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It is necessary to expand extensive chronic clinical trials to evaluate the long-term safety, efficacy, and optimal dosing of polyphenols, examine gene-diet and microbiota-polyphenol interactions to elucidate inter-individual variability, develop innovative delivery systems to improve bioavailability and facilitate clinical translation, and clarify potential drug interactions and safety in vulnerable populations

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In a research context, the KLOW blend serves as a multifaceted tool to investigate the potential synergistic effects of these molecular pathways simultaneously on cellular healing models, gene expression, and tissue regeneration assays