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After 6 weeks of treatment, mice treated with gemcitabine, either as a single agent or in dual combination with HGF or c-MET inhibition, exhibited smaller tumours than IgG-treated controls, but statistically significant differences were only observed in G + Ci and the triple therapy (Hi + Ci + G) groups

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A carboxylterminal determinant of the neuronal glutamate transporter, EAAC1, is required for plateletderived growth factordependent trafficking