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The concept born by Robert (epithelium) [16,17] and Szabo (endothelium) [18,19,20,21] holds stomach integrity maintenance that should be translated to other organ healing as well by cytoprotective agents application [16,17,18,19,20,21]

In general, iron overload in cells, decreased GPX4 and xCT expression, activation of acylCoA synthetase long-chain family member-4 (ACSL4) and lysophosphatidylcholine acyltransferase-3, and an increase in lipid peroxidation are the four main mechanisms that induce ferroptosis [82,83,84]

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