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If the framework identifies the pattern but not the source

doi: 10.1186/1743-7075-7-55

7779, Jul

BCL-2-Selective BH3 Mimetic ABT-199 Is a Potent Agent For Acute Myeloid Leukemia

It was shown in vitro using ZF cell lines that constant ACTH treatment led to larger increase in pCREB and steroidogenic gene transcription at the start of treatment but the cells became unresponsive to the stimuli over time (158)
Insulin Receptor Cross-Reactivity: At high concentrations, IGF-I can activate insulin receptors