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In this review, we aimed to summarize the changes in endogenous GLP-1 levels and their association with weight loss after MBS, describe the effects of GLP-1-RA use on weight loss after MBS, and emphasize metabolic adaptations in light of the recent literature

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(For a detailed history, I recommend Megan Molteni and Elaine Chens piece for STAT.) The benefits of these drugs are undeniable, but when it comes to evaluating their risks, we run into challenges that researchers are familiar with but that the public at large may not be aware of

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GLP-1 weight loss medications have transformed obesity treatment, but their price tag raises questions