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Figure 1 3 Endometriosis microenvironment: ironredox dysregulation and cell-death priming Most of the iron in the human body is contained within circulating red blood cells, where it plays pivotal roles in oxygen transport, metabolic reactions, and DNA synthesis (15)
Data from various studies on respiratory viruses raise the speculation that antibodies elicited against SARS-CoV-2 and during COVID-19 recovery could potentially exacerbate the infection through ADE at sub-neutralizing concentrations
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In addition, fumarate inhibits TET enzymes, which stimulate EMT, leading to cancer metastasis 131,132
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Caspases comprise a family of cysteine proteases composed of 12 members in humans [132]
