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Figures 1, 2, 3, 4, 5, 6 and 7 were created using Figdraw ( under the following copyright licenses: ORIOA4c1d0 (Figure 1), YAPUTa8433 (Figure 2), OWTTPb979d (Figure 3), UYWWS424ef (Figure 4), WSRPR86373 (Figure 5), UTIRT1b244 (Figure 6), and YPIUWa47ea (Figure 7)