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doi: 10.3389/fanim.2025.1669519 Received 19 July 2025 Accepted 04 September 2025 Published 18 September 2025 Volume 6 - 2025 Edited by Muhammet Rasit Ugur, IVF Michigan Fertility Centers, United States Reviewed by Tlou Christopher Kujoana, University of South Africa, South Africa

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In summary, this experimental design comprehensively combined behavioral pain assays and molecular analyses to evaluate the therapeutic potential of DALDA in mitigating frostbite-induced neuropathic pain and its associated oxidative and inflammatory responses in rats [2]

This treatment concurrently alleviated the reliance on protein (RQ = 0.8), particularly when CaAKG was consumed along food at multiple times within a day to sustain this effect (Fig