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Published in vitro work has characterized 5-Amino-1MQ as a competitive NNMT inhibitor with low micromolar potency against the recombinant enzyme, and as a cell-permeable agent that suppresses NNMT activity in cultured 3T3-L1 adipocytes at micromolar concentrations [1]
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[DOI] [PubMed] [Google Scholar] 110.Lieverse RJ, Jansen JB, Masclee AA, Lamers CB
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