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2) substitution of a d-amino acid at the N-terminal position

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Intravenous administration might be better in some cases

The 2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects

[1] [2] However, longstanding neurological complications, such as peripheral neuropathy or cognitive changes, may require three to six months of consistent treatment before significant improvement occurs, and some damage may be irreversible if treatment is delayed

Patients should report severe abdominal pain or bloody stools immediately