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Finally, a number of inherited mutations in genes involved in carnitine shuttling and fatty acid oxidation pathways do not systematically result in carnitine depletion (such that carnitine supplementation may not help mitigate the symptoms) but lead to abnormal profiles of acylcarnitine esters in blood (35, 40)

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Clinical data show that continuous use of L-Carnitine Cream for 8 weeks can reduce local fat thickness by 12%-18% and shrink waist circumference by 2-3 cm