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Lipedema Causes: Genetics and Lifestyle Impact Key Takeaways Recognize Symptoms Early: Early identification of lipedema symptoms, such as disproportionate fat distribution in the legs and arms, primary lipodystrophy, and pathological lipid profiles in adipose tissue, can lead to better management and treatment outcomes, including liposuction

PNAS Nexus 4 , pgaf042 (2025)

[DOI] [PubMed] [Google Scholar] Samuni Y, Goldstein S, Dean OM, Berk M

Directed Evolution of a Cytochrome P450 Carbene Transferase for Selective Functionalization of Cyclic Compounds

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