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Management: Use cautiously and under medical guidance if prolonged therapy is needed

Zonisamide for weight loss in obese adults: a randomized controlled trial

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AOD-9604, a synthetic growth hormone analogue, has been studied as an investigational agent for several indications 1

The GLP-1 and GIP arms slow gastric emptying and blunt appetite (that is where nausea comes from), while the glucagon arm nudges energy expenditure and hepatic fat handling
