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AOD9604 and Energy Balance Research In obese ob/ob and lean C57BL/6J mice treated for 14 days via mini-osmotic pumps, AOD9604 significantly reduced body weight gain in obese mice, associated with increased in vivo fat oxidation and increased plasma glycerol levels as an index of enhanced lipolysis without the hyperglycaemia or reduced insulin secretion associated with intact hGH treatment

SIRT6 expression and oxidative DNA damage in individuals with prediabetes and type 2 diabetes mellitus

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However, compared to a human observer, Pathfinder allows a strict objectivity in the classification of search strategies

3f), but with a circadian shift compared to the same mice measured 6 months before (Supplementary Fig