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In the dataset from Govaere et al., more than 200 individual liver biopsies from patients were histologically scored to determine MASLD/MASH stage, followed by RNA-seq for transcriptomic profiling (46) (Figure 6C)

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N.ZhangL.GuramK.SharmaS.et al

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Researchers are particularly interested in its ability to promote functional recovery even in challenging injury models

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ATP-binding cassette transporter A4 (ABCA4) facilitates the transport of atRAL from the outer segment discs of photoreceptors to the cytoplasm, while all-trans retinol dehydrogenase 8 (RDH8) catalyses the conversion of atRAL back to all-trans retinol (260)

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